A multipronged approach unravels unprecedented protein–protein interactions in the human 2-oxoglutarate dehydrogenase multienzyme complex

The human 2-oxoglutaric acid dehydrogenase complex (hOGDHc) plays a pivotal role in the tricarboxylic acid (TCA) cycle, and its diminished activity is associated with neurodegenerative diseases. The hOGDHc comprises three components, hE1o, hE2o, and hE3, and we recently reported functionally active...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Zhou, Jieyu, Yang, Luying, Ozohanics, Oliver, Zhang, Xu, Wang, Junjie, Ambrus, Attila, Arjunan, Palaniappa, Brukh, Roman, Nemeria, Natalia S., Furey, William, Jordan, Frank
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2018
נושאים:
Enzymology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302161/
https://ncbi.nlm.nih.gov/pubmed/30323066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005432
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