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How specific is CRISPR/Cas9 really?
The specificity of RNA-guided nucleases has gathered considerable interest as they become broadly applied to basic research and therapeutic development. Reports of the simple generation of animal models and genome engineering of cells raised questions about targeting precision. Conflicting early rep...
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| Udgivet i: | Curr Opin Chem Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4684463/ https://ncbi.nlm.nih.gov/pubmed/26517564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2015.10.001 |
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