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How specific is CRISPR/Cas9 really?
The specificity of RNA-guided nucleases has gathered considerable interest as they become broadly applied to basic research and therapeutic development. Reports of the simple generation of animal models and genome engineering of cells raised questions about targeting precision. Conflicting early rep...
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| Publicado no: | Curr Opin Chem Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4684463/ https://ncbi.nlm.nih.gov/pubmed/26517564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2015.10.001 |
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