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A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture
Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided nucleases have gathered considerable excitement as a tool for genome engineering. However, questions remain about the specificity of target site recognition. Cleavage specificity is typically evaluated by low throughput ass...
Zapisane w:
| Wydane w: | Nucleic Acids Res |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4381059/ https://ncbi.nlm.nih.gov/pubmed/25712100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv137 |
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