Loss of hepatocyte ERBB3 but not EGFR impairs hepatocarcinogenesis

Epidermal growth factor receptor (EGFR) and ERBB3 have been implicated in hepatocellular carcinogenesis (HCC). However, it is not known whether altering the activity of either EGFR or ERBB3 affects HCC development. We now show that Egfr(Dsk5) mutant mice, which have a gain-of-function allele that in...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Gastrointest Liver Physiol
Egile Nagusiak: Scheving, Lawrence A., Zhang, Xiuqi, Stevenson, Mary C., Weintraub, Michael A., Abbasi, Annam, Clarke, Andrea M., Threadgill, David W., Russell, William E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2015
Gaiak:
Liver and Biliary Tract Physiology/Pathophysiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683301/
https://ncbi.nlm.nih.gov/pubmed/26492920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00089.2015
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