Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression

Glucocorticoid signaling regulates target genes by multiple mechanisms, including the repression of transcriptional activities of nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) though direct protein-protein interactions and subsequent O-GlcNAcylation of RNA polymerase II (pol II)...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Stivers, Peter J., Harmonay, Lauren, Hicks, Alexandra, Mehmet, Huseyin, Morris, Melody, Robinson, Gain M., Strack, Peter R., Savage, Mary J., Zaller, Dennis M., Zwierzynski, Izabela, Brandish, Philip E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682863/
https://ncbi.nlm.nih.gov/pubmed/26670328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145151
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