SCF(β-TRCP) promotes cell growth by targeting PR-Set7/Set8 for degradation

The Set8/PR-Set7/KMT5a methyltransferase plays critical roles in governing transcriptional regulation, cell cycle progression and tumorigenesis. Although CRL4(Cdt2) was reported to regulate Set8 stability, deleting the PIP motif only led to partial resistance to ultraviolet-induced degradation of Se...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Wang, Zhiwei, Dai, Xiangpeng, Zhong, Jiateng, Inuzuka, Hiroyuki, Wan, Lixin, Li, Xiaoning, Wang, Lixia, Ye, Xiantao, Sun, Liankun, Gao, Daming, Zou, Lee, Wei, Wenyi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682171/
https://ncbi.nlm.nih.gov/pubmed/26666832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10185
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker