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Reprogramming of Polycomb-Mediated Gene Silencing in Embryonic Stem Cells by the miR-290 Family and the Methyltransferase Ash1l

Members of the miR-290 family are the most abundantly expressed microRNAs (miRNAs) in mouse embryonic stem cells (ESCs). They regulate aspects of differentiation, pluripotency, and proliferation of ESCs, but the molecular program that they control has not been fully delineated. In the absence of Dic...

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Vydáno v:Stem Cell Reports
Hlavní autoři: Kanellopoulou, Chryssa, Gilpatrick, Timothy, Kilaru, Gokhul, Burr, Patrick, Nguyen, Cuong K., Morawski, Aaron, Lenardo, Michael J., Muljo, Stefan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682067/
https://ncbi.nlm.nih.gov/pubmed/26549848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.10.001
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