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Interactions Involved in pH Protection of the Alphavirus Fusion Protein

The alphavirus membrane protein E1 mediates low pH-triggered fusion of the viral and endosome membranes during virus entry. During virus biogenesis E1 associates as a heterodimer with the transmembrane protein p62. Late in the secretory pathway, cellular furin cleaves p62 to the mature E2 protein an...

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Bibliografiske detaljer
Udgivet i:Virology
Main Authors: Fields, Whitney, Kielian, Margaret
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4679575/
https://ncbi.nlm.nih.gov/pubmed/26433749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.08.028
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