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Cross-Inhibition of Chikungunya Virus Fusion and Infection by Alphavirus E1 Domain III Proteins

Alphaviruses are small enveloped RNA viruses that include important emerging human pathogens, such as chikungunya virus (CHIKV). These viruses infect cells via a low-pH-triggered membrane fusion reaction, making this step a potential target for antiviral therapies. The E1 fusion protein inserts into...

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Detalhes bibliográficos
Main Authors: Sánchez-San Martín, Claudia, Nanda, Soumya, Zheng, Yan, Fields, Whitney, Kielian, Margaret
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700285/
https://ncbi.nlm.nih.gov/pubmed/23637415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00814-13
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