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A Key Interaction between the Alphavirus Envelope Proteins Responsible for Initial Dimer Dissociation during Fusion

Alphaviruses such as Semliki Forest virus (SFV) are enveloped viruses whose surface is covered by an organized lattice composed of trimers of E2-E1 heterodimers. The E1 envelope protein, a class II fusion protein, contains the hydrophobic fusion loop and refolds to drive virus fusion with the endoso...

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Main Authors: Fields, Whitney, Kielian, Margaret
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624238/
https://ncbi.nlm.nih.gov/pubmed/23325694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03310-12
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