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Interactions Involved in pH Protection of the Alphavirus Fusion Protein
The alphavirus membrane protein E1 mediates low pH-triggered fusion of the viral and endosome membranes during virus entry. During virus biogenesis E1 associates as a heterodimer with the transmembrane protein p62. Late in the secretory pathway, cellular furin cleaves p62 to the mature E2 protein an...
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| Published in: | Virology |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4679575/ https://ncbi.nlm.nih.gov/pubmed/26433749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.08.028 |
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