Exenatide Activates the APPL1-AMPK-PPARα Axis to Prevent Diabetic Cardiomyocyte Apoptosis

Objective. To investigate the effect and mechanism of the exenatide on diabetic cardiomyopathy. Methods. Rats were divided into control group, diabetes group (D), diabetes treated with insulin (DI) group, and diabetes treat with exenatide (DE) group. We detected apoptosis rate by TUNEL, the adiponec...

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Bibliographic Details
Published in:J Diabetes Res
Main Authors: XiaoTian, Lei, QiNan, Wu, XiaGuang, Gan, WuQuan, Deng, Bing, Chen, ZiWen, Liang
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677202/
https://ncbi.nlm.nih.gov/pubmed/26759813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4219735
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