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Exenatide Activates the APPL1-AMPK-PPARα Axis to Prevent Diabetic Cardiomyocyte Apoptosis

Objective. To investigate the effect and mechanism of the exenatide on diabetic cardiomyopathy. Methods. Rats were divided into control group, diabetes group (D), diabetes treated with insulin (DI) group, and diabetes treat with exenatide (DE) group. We detected apoptosis rate by TUNEL, the adiponec...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: XiaoTian, Lei, QiNan, Wu, XiaGuang, Gan, WuQuan, Deng, Bing, Chen, ZiWen, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677202/
https://ncbi.nlm.nih.gov/pubmed/26759813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4219735
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