Exenatide Activates the APPL1-AMPK-PPARα Axis to Prevent Diabetic Cardiomyocyte Apoptosis

Objective. To investigate the effect and mechanism of the exenatide on diabetic cardiomyopathy. Methods. Rats were divided into control group, diabetes group (D), diabetes treated with insulin (DI) group, and diabetes treat with exenatide (DE) group. We detected apoptosis rate by TUNEL, the adiponec...

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Vydáno v:J Diabetes Res
Hlavní autoři: XiaoTian, Lei, QiNan, Wu, XiaGuang, Gan, WuQuan, Deng, Bing, Chen, ZiWen, Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677202/
https://ncbi.nlm.nih.gov/pubmed/26759813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4219735
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