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Par-4/NF-κB Mediates the Apoptosis of Islet β Cells Induced by Glucolipotoxicity
Apoptosis of islet β cells is a primary pathogenic feature of type 2 diabetes, and ER stress and mitochondrial dysfunction play important roles in this process. Previous research has shown that prostate apoptosis response-4 (Par-4)/NF-κB induces cancer cell apoptosis through endoplasmic reticulum (E...
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| Publicado no: | J Diabetes Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4906207/ https://ncbi.nlm.nih.gov/pubmed/27340675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4692478 |
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