Exenatide reduces cardiomyocyte apoptosis by stimulating adiponectin secretion and activating APPL1-AMPK-PPARα axis

BACKGROUND: To explore the mechanism that exenatide reduces cardiomyocyte apoptosis via the adiponectin pathway in vitro. METHODS: Cardiomyocytes were randomly divided into the control group (group C), diabetic group (group D), diabetic + exenatide treatment group (group DE), diabetic + exenatide tr...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Lei, Xiaotian, Wu, Qinan, Leng, Weiling, Wu, Minxia, Chen, Liu, Liang, Ziwen
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694259/
https://ncbi.nlm.nih.gov/pubmed/31475196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.06.17
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