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An APPL1-AMPK signaling axis mediates beneficial metabolic effects of adiponectin in the heart
Adiponectin promotes cardioprotection by various mechanisms, and this study used primary cardiomyocytes and the isolated working perfused heart to investigate cardiometabolic effects. We show in adult cardiomyocytes that adiponectin increased CD36 translocation and fatty acid uptake as well as insul...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980363/ https://ncbi.nlm.nih.gov/pubmed/20739511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00086.2010 |
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