An APPL1-AMPK signaling axis mediates beneficial metabolic effects of adiponectin in the heart

Adiponectin promotes cardioprotection by various mechanisms, and this study used primary cardiomyocytes and the isolated working perfused heart to investigate cardiometabolic effects. We show in adult cardiomyocytes that adiponectin increased CD36 translocation and fatty acid uptake as well as insul...

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Main Authors: Fang, Xiangping, Palanivel, Rengasamy, Cresser, Justin, Schram, Kristin, Ganguly, Riya, Thong, Farah S. L., Tuinei, Joseph, Xu, Aimin, Abel, E. Dale, Sweeney, Gary
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980363/
https://ncbi.nlm.nih.gov/pubmed/20739511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00086.2010
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