Endoplasmic Reticulum-Associated rht-PA Processing in CHO Cells: Influence of Mild Hypothermia and Specific Growth Rates in Batch and Chemostat Cultures

BACKGROUND: Chinese hamster ovary (CHO) cells are the main host for producing recombinant proteins with human therapeutic applications mainly because of their capability to perform proper folding and glycosylation processes. In addition, mild hypothermia is one of the main strategies for maximising...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Vergara, Mauricio, Berrios, Julio, Martínez, Irene, Díaz-Barrera, Alvaro, Acevedo, Cristian, Reyes, Juan G., Gonzalez, Ramon, Altamirano, Claudia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676689/
https://ncbi.nlm.nih.gov/pubmed/26659083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144224
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi