Defining the Role of Tyrosine and Rational Tuning of Oxidase Activity by Genetic Incorporation of Unnatural Tyrosine Analogs

[Image: see text] While a conserved tyrosine (Tyr) is found in oxidases, the roles of phenol ring pK(a) and reduction potential in O(2) reduction have not been defined despite many years of research on numerous oxidases and their models. These issues represent major challenges in our understanding o...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Yu, Yang, Lv, Xiaoxuan, Li, Jiasong, Zhou, Qing, Cui, Chang, Hosseinzadeh, Parisa, Mukherjee, Arnab, Nilges, Mark J., Wang, Jiangyun, Lu, Yi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2015
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676419/
https://ncbi.nlm.nih.gov/pubmed/25672571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5109936
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia