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Direct EPR Observation of a Tyrosyl Radical in a Functional Oxidase Model in Myoglobin during both H(2)O(2) and O(2) Reactions

Tyrosine is a conserved redox-active amino acid that plays important roles in heme-copper oxidases (HCO). Despite the widely proposed mechanism that involves a tyrosyl radical, its direct observation under O(2) reduction condition remains elusive. Using a functional oxidase model in myoglobin called...

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Detalhes bibliográficos
Main Authors: Yu, Yang, Mukherjee, Arnab, Nilges, Mark J., Hosseinzadeh, Parisa, Miner, Kyle D., Lu, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955430/
https://ncbi.nlm.nih.gov/pubmed/24383850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4091885
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