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Significant improvement of oxidase activity through the genetic incorporation of a redox-active unnatural amino acid
While nature employs various covalent and non-covalent strategies to modulate tyrosine (Y) redox potential and pK (a) in order to optimize enzyme activities, such approaches have not been systematically applied for the design of functional metalloproteins. Through the genetic incorporation of 3-meth...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4583198/ https://ncbi.nlm.nih.gov/pubmed/26417427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01126d |
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