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Significant improvement of oxidase activity through the genetic incorporation of a redox-active unnatural amino acid

While nature employs various covalent and non-covalent strategies to modulate tyrosine (Y) redox potential and pK (a) in order to optimize enzyme activities, such approaches have not been systematically applied for the design of functional metalloproteins. Through the genetic incorporation of 3-meth...

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Bibliografski detalji
Izdano u:Chem Sci
Glavni autori: Yu, Yang, Zhou, Qing, Wang, Li, Liu, Xiaohong, Zhang, Wei, Hu, Meirong, Dong, Jianshu, Li, Jiasong, Lv, Xiaoxuan, Ouyang, Hanlin, Li, Han, Gao, Feng, Gong, Weimin, Lu, Yi, Wang, Jiangyun
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583198/
https://ncbi.nlm.nih.gov/pubmed/26417427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01126d
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