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Conformational Flip of Nonactivated HCN2 Channel Subunits Evoked by Cyclic Nucleotides
Hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels are tetrameric proteins that evoke electrical rhythmicity in specialized neurons and cardiomyocytes. The channels are activated by hyperpolarizing voltage but are also receptors for the intracellular ligand adenosine-3′,5′-cyclic...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4675818/ https://ncbi.nlm.nih.gov/pubmed/26636938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.08.054 |
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