Alpha imaging confirmed efficient targeting of CD45-positive cells after astatine-211 ((211)At)-radioimmunotherapy for hematopoietic cell transplantation

Alpha-radioimmunotherapy targeting CD45 may substitute for total body irradiation in hematopoietic cell transplantation (HCT) preparative regimens for lymphoma. Our goal was to optimize the anti-CD45 monoclonal antibody (MAb; CA12.10C12) protein dose for astatine-211 ((211)At)-radioimmunotherapy, ex...

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Bibliografski detalji
Izdano u:J Nucl Med
Glavni autori: Frost, Sofia H.L., Miller, Brian W., Bäck, Tom A., Santos, Erlinda B., Hamlin, Donald K., Knoblaugh, Sue E., Frayo, Shani L., Kenoyer, Aimee L., Storb, Rainer, Press, Oliver W., Wilbur, D. Scott, Pagel, John M., Sandmaier, Brenda M.
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675464/
https://ncbi.nlm.nih.gov/pubmed/26338894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.162388
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