Alpha imaging confirmed efficient targeting of CD45-positive cells after astatine-211 ((211)At)-radioimmunotherapy for hematopoietic cell transplantation

Alpha-radioimmunotherapy targeting CD45 may substitute for total body irradiation in hematopoietic cell transplantation (HCT) preparative regimens for lymphoma. Our goal was to optimize the anti-CD45 monoclonal antibody (MAb; CA12.10C12) protein dose for astatine-211 ((211)At)-radioimmunotherapy, ex...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Nucl Med
Prif Awduron: Frost, Sofia H.L., Miller, Brian W., Bäck, Tom A., Santos, Erlinda B., Hamlin, Donald K., Knoblaugh, Sue E., Frayo, Shani L., Kenoyer, Aimee L., Storb, Rainer, Press, Oliver W., Wilbur, D. Scott, Pagel, John M., Sandmaier, Brenda M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675464/
https://ncbi.nlm.nih.gov/pubmed/26338894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.162388
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