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Identifying representative drug resistant mutants of HIV

BACKGROUND: Drug resistance is one of the most important causes for failure of anti-AIDS treatment. During therapy, multiple mutations accumulate in the HIV genome, eventually rendering the drugs ineffective in blocking replication of the mutant virus. The huge number of possible mutants precludes e...

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書目詳細資料
發表在:BMC Bioinformatics
Main Authors: Yu, Xiaxia, Weber, Irene T, Harrison, Robert W
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674865/
https://ncbi.nlm.nih.gov/pubmed/26678327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S17-S1
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