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Identifying representative drug resistant mutants of HIV

BACKGROUND: Drug resistance is one of the most important causes for failure of anti-AIDS treatment. During therapy, multiple mutations accumulate in the HIV genome, eventually rendering the drugs ineffective in blocking replication of the mutant virus. The huge number of possible mutants precludes e...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Yu, Xiaxia, Weber, Irene T, Harrison, Robert W
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674865/
https://ncbi.nlm.nih.gov/pubmed/26678327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S17-S1
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