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Identifying representative drug resistant mutants of HIV

BACKGROUND: Drug resistance is one of the most important causes for failure of anti-AIDS treatment. During therapy, multiple mutations accumulate in the HIV genome, eventually rendering the drugs ineffective in blocking replication of the mutant virus. The huge number of possible mutants precludes e...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Yu, Xiaxia, Weber, Irene T, Harrison, Robert W
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674865/
https://ncbi.nlm.nih.gov/pubmed/26678327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S17-S1
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