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Genetic Resistance Determinants, In Vitro Time-Kill Curve Analysis and Pharmacodynamic Functions for the Novel Topoisomerase II Inhibitor ETX0914 (AZD0914) in Neisseria gonorrhoeae

Resistance in Neisseria gonorrhoeae to all available therapeutic antimicrobials has emerged and new efficacious drugs for treatment of gonorrhea are essential. The topoisomerase II inhibitor ETX0914 (also known as AZD0914) is a new spiropyrimidinetrione antimicrobial that has different mechanisms of...

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Bibliografske podrobnosti
izdano v:Front Microbiol
Main Authors: Foerster, Sunniva, Golparian, Daniel, Jacobsson, Susanne, Hathaway, Lucy J., Low, Nicola, Shafer, William M., Althaus, Christian L., Unemo, Magnus
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674575/
https://ncbi.nlm.nih.gov/pubmed/26696986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.01377
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