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Genetic Resistance Determinants, In Vitro Time-Kill Curve Analysis and Pharmacodynamic Functions for the Novel Topoisomerase II Inhibitor ETX0914 (AZD0914) in Neisseria gonorrhoeae

Resistance in Neisseria gonorrhoeae to all available therapeutic antimicrobials has emerged and new efficacious drugs for treatment of gonorrhea are essential. The topoisomerase II inhibitor ETX0914 (also known as AZD0914) is a new spiropyrimidinetrione antimicrobial that has different mechanisms of...

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書目詳細資料
發表在:Front Microbiol
Main Authors: Foerster, Sunniva, Golparian, Daniel, Jacobsson, Susanne, Hathaway, Lucy J., Low, Nicola, Shafer, William M., Althaus, Christian L., Unemo, Magnus
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674575/
https://ncbi.nlm.nih.gov/pubmed/26696986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.01377
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