Genetic Resistance Determinants, In Vitro Time-Kill Curve Analysis and Pharmacodynamic Functions for the Novel Topoisomerase II Inhibitor ETX0914 (AZD0914) in Neisseria gonorrhoeae

Resistance in Neisseria gonorrhoeae to all available therapeutic antimicrobials has emerged and new efficacious drugs for treatment of gonorrhea are essential. The topoisomerase II inhibitor ETX0914 (also known as AZD0914) is a new spiropyrimidinetrione antimicrobial that has different mechanisms of...

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Bibliografische gegevens
Gepubliceerd in:Front Microbiol
Hoofdauteurs: Foerster, Sunniva, Golparian, Daniel, Jacobsson, Susanne, Hathaway, Lucy J., Low, Nicola, Shafer, William M., Althaus, Christian L., Unemo, Magnus
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2015
Onderwerpen:
Microbiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674575/
https://ncbi.nlm.nih.gov/pubmed/26696986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.01377
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