Multidrug-Resistant Neisseria gonorrhoeae Isolates from Nanjing, China, Are Sensitive to Killing by a Novel DNA Gyrase Inhibitor, ETX0914 (AZD0914)

We tested the activity of ETX0914 against 187 Neisseria gonorrhoeae isolates from men with urethritis in Nanjing, China, in 2013. The MIC(50), MIC(90), and MIC range for ETX0914 were 0.03 μg/ml, 0.06 μg/ml, and ≤0.002 to 0.125 μg/ml, respectively. All isolates were resistant to ciprofloxacin, and 36...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Su, Xiao-Hong, Wang, Bao-Xi, Le, Wen-Jing, Liu, Yu-Rong, Wan, Chuan, Li, Sai, Alm, Richard A., Mueller, John P., Rice, Peter A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Susceptibility
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704236/
https://ncbi.nlm.nih.gov/pubmed/26482313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01211-15
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