A Novel Time-Dependent CENP-E Inhibitor with Potent Antitumor Activity

Centromere-associated protein E (CENP-E) regulates both chromosome congression and the spindle assembly checkpoint (SAC) during mitosis. The loss of CENP-E function causes chromosome misalignment, leading to SAC activation and apoptosis during prolonged mitotic arrest. Here, we describe the biologic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ohashi, Akihiro, Ohori, Momoko, Iwai, Kenichi, Nambu, Tadahiro, Miyamoto, Maki, Kawamoto, Tomohiro, Okaniwa, Masanori
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674098/
https://ncbi.nlm.nih.gov/pubmed/26649895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144675
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados