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Peripheral challenge with a viral mimic upregulates expression of the complement genes in the hippocampus

Peripheral challenge with a viral mimetic, polyinosinic-polycytidylic acid (PIC) induces hippocampal hyperexcitability in mice. Here, we characterized this hippocampal response through a whole genome transcriptome analysis. Intraperitoneal injection of PIC resulted in temporal dysregulation of 625 g...

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Bibliografske podrobnosti
izdano v:J Neuroimmunol
Main Authors: Michalovicz, Lindsay T., Lally, Brent, Konat, Gregory W.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673984/
https://ncbi.nlm.nih.gov/pubmed/26198930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2015.06.003
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