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Peripherally restricted acute phase response to a viral mimic alters hippocampal gene expression

We have previously shown that peripherally restricted acute phase response (APR) elicited by intraperitoneal (i.p.) injection of a viral mimic, polyinosinic-polycytidylic acid (PIC), renders the brain hypersusceptible to excitotoxic insult as seen from profoundly exacerbated kainic acid (KA)-induced...

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Detalhes bibliográficos
Publicado no:Metab Brain Dis
Main Authors: Michalovicz, Lindsay T., Konat, Gregory W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343041/
https://ncbi.nlm.nih.gov/pubmed/24363211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-013-9471-6
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