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Resolution of stepwise cooperativities of copper binding by the homotetrameric copper sensitive operon repressor (CsoR): Impact on structure and stability()
The cooperativity of ligand binding is central to biological regulation and new approaches are needed to quantify these allosteric relationships. Herein, we exploit a suite of mass spectrometry (MS) experiments to provide novel insights into homotropic Cu-binding cooperativity, gas-phase stabilities...
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| 出版年: | Angew Chem Int Ed Engl |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4673887/ https://ncbi.nlm.nih.gov/pubmed/26332992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201506349 |
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