Cu(I)-mediated Allosteric Switching in a Copper-sensing Operon Repressor (CsoR)

The copper-sensing operon repressor (CsoR) is representative of a major Cu(I)-sensing family of bacterial metalloregulatory proteins that has evolved to prevent cytoplasmic copper toxicity. It is unknown how Cu(I) binding to tetrameric CsoRs mediates transcriptional derepression of copper resistance...

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Detalhes bibliográficos
Main Authors: Chang, Feng-Ming James, Coyne, H. Jerome, Cubillas, Ciro, Vinuesa, Pablo, Fang, Xianyang, Ma, Zhen, Ma, Dejian, Helmann, John D., García-de los Santos, Alejandro, Wang, Yun-Xing, Dann, Charles E., Giedroc, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4081955/
https://ncbi.nlm.nih.gov/pubmed/24831014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.556704
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