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Backbone resonance assignments of the homotetrameric (48 kD) copper sensor CsoR from Geobacillus thermodenitrificans in the apo- and Cu(I)-bound states: Insights into copper-mediated allostery

Prokaryotes are highly susceptible to exogenous copper and employ metalloregulatory proteins to control the intracellular concentration. CsoR (copper-sensitive operon repressor) is one such protein that represses transcription of a Cu(I)-effluxing ATPase in its apo form. Cu(I)-binding leads to trans...

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Detalhes bibliográficos
Main Authors: Coyne, H. Jerome, Giedroc, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586942/
https://ncbi.nlm.nih.gov/pubmed/23001947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-012-9428-4
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