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Two Scaffolds from Two Flips: (α,β)/(β,γ) CH(2)/NH “Met-Im” Analogues of dTTP
Novel α,β-CH(2) and β,γ-NH (1a) or α,β-NH and β,γ-CH(2) (1b) “Met-Im” dTTPs were synthesized via monodemethylation of triethyl-dimethyl phosphorimido-bisphosphonate synthons (4a, 4b), formed via a base-induced [1,3]-rearrangement of precursors (3a, 3b) in a reaction with dimethyl or diethyl phosphoc...
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| Publicat a: | Org Lett |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4672865/ https://ncbi.nlm.nih.gov/pubmed/25970636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b00799 |
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