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Two Scaffolds from Two Flips: (α,β)/(β,γ) CH(2)/NH “Met-Im” Analogues of dTTP

Novel α,β-CH(2) and β,γ-NH (1a) or α,β-NH and β,γ-CH(2) (1b) “Met-Im” dTTPs were synthesized via monodemethylation of triethyl-dimethyl phosphorimido-bisphosphonate synthons (4a, 4b), formed via a base-induced [1,3]-rearrangement of precursors (3a, 3b) in a reaction with dimethyl or diethyl phosphoc...

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Bibliografiske detaljer
Udgivet i:Org Lett
Main Authors: Kadina, Anastasia P., Kashemirov, Boris A., Oertell, Keriann, Batra, Vinod K., Wilson, Samuel H., Goodman, Myron F., McKenna, Charles E.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672865/
https://ncbi.nlm.nih.gov/pubmed/25970636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b00799
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