Comparison of Gene Expression by Sheep and Human Blood Stimulated with the TLR4 Agonists Lipopolysaccharide and Monophosphoryl Lipid A

BACKGROUND: Animal models that mimic human biology are important for successful translation of basic science discoveries into the clinical practice. Recent studies in rodents have demonstrated the efficacy of TLR4 agonists as immunomodulators in models of infection. However, rodent models have been...

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Pubblicato in:PLoS One
Autori principali: Enkhbaatar, Perenlei, Nelson, Christina, Salsbury, John R., Carmical, Joseph R., Torres, Karen E. O., Herndon, David, Prough, Donald S., Luan, Liming, Sherwood, Edward R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671644/
https://ncbi.nlm.nih.gov/pubmed/26640957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144345
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