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Charting oxidized methylcytosines at base resolution
DNA cytosine methylation (5-methylcytosines) represents a key epigenetic mark and is required for normal development. Iterative oxidation of 5mC by TET family of DNA dioxygenases generates three oxidized nucleotides, 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxycytosine (5caC...
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| Publicat a: | Nat Struct Mol Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4671372/ https://ncbi.nlm.nih.gov/pubmed/26333715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3071 |
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