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Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution

Although various methods have been developed for sequencing cytosine modifications, it is still challenging for specific and quantitative sequencing of individual modification at base-resolution. For example, to obtain both true 5-methylcytosine (5mC) and true 5-hydroxymethylcytosine (5hmC) informat...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Yibin, Hu, Zhiyuan, Cheng, Jingfei, Siejka-Zielińska, Paulina, Chen, Jinfeng, Inoue, Masato, Ahmed, Ahmed Ashour, Song, Chun-Xiao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840749/
https://ncbi.nlm.nih.gov/pubmed/33504799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-20920-2
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