Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution

Although various methods have been developed for sequencing cytosine modifications, it is still challenging for specific and quantitative sequencing of individual modification at base-resolution. For example, to obtain both true 5-methylcytosine (5mC) and true 5-hydroxymethylcytosine (5hmC) informat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Liu, Yibin, Hu, Zhiyuan, Cheng, Jingfei, Siejka-Zielińska, Paulina, Chen, Jinfeng, Inoue, Masato, Ahmed, Ahmed Ashour, Song, Chun-Xiao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840749/
https://ncbi.nlm.nih.gov/pubmed/33504799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-20920-2
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