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Protein interactions at oxidized 5-methylcytosine bases

5-methylcytosine (5mC), the major modified DNA base in mammalian cells, can be oxidized enzymatically to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) by the Ten-Eleven-Translocation (TET) family of proteins. Whereas 5fC and 5caC are recognized and removed by b...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Pfeifer, Gerd P., Szabó, Piroska E., Song, Jikui
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007358/
https://ncbi.nlm.nih.gov/pubmed/31401118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.07.039
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