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Protein interactions at oxidized 5-methylcytosine bases
5-methylcytosine (5mC), the major modified DNA base in mammalian cells, can be oxidized enzymatically to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) by the Ten-Eleven-Translocation (TET) family of proteins. Whereas 5fC and 5caC are recognized and removed by b...
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| Veröffentlicht in: | J Mol Biol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7007358/ https://ncbi.nlm.nih.gov/pubmed/31401118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.07.039 |
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