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Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
Genome-wide erasure of DNA cytosine-5 methylation has been reported to occur along the paternal pronucleus in fertilized oocytes in an apparently replication-independent manner, but the mechanism of this reprogramming process has remained enigmatic. Recently, considerable amounts of 5-hydroxymethylc...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048122/ https://ncbi.nlm.nih.gov/pubmed/21321204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014033108 |
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