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Deleterious effects of endocrine disruptors are corrected in the mammalian germline by epigenome reprogramming
BACKGROUND: Exposure to environmental endocrine-disrupting chemicals during pregnancy reportedly causes transgenerationally inherited reproductive defects. We hypothesized that to affect the grandchild, endocrine-disrupting chemicals must alter the epigenome of the germ cells of the in utero-exposed...
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出版年: | Genome Biol |
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主要な著者: | , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
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BioMed Central
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376074/ https://ncbi.nlm.nih.gov/pubmed/25853433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0619-z |
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