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Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation

Ten-eleven translocation 1–3 (Tet1–3) proteins have recently been discovered in mammalian cells to be members of a family of DNA hydroxylases that possess enzymatic activity toward the methyl mark on the 5-position of cytosine (5-methylcytosine [5mC]), a well-characterized epigenetic modification th...

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Detalhes bibliográficos
Main Authors: Wu, Hao, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243055/
https://ncbi.nlm.nih.gov/pubmed/22156206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.179184.111
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