S100B inhibition reduces behavioral and pathologic changes in experimental traumatic brain injury

Neuroinflammation following traumatic brain injury (TBI) is increasingly recognized to contribute to chronic tissue loss and neurologic dysfunction. Circulating levels of S100B increase after TBI and have been used as a biomarker. S100B is produced by activated astrocytes and can promote microglial...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cereb Blood Flow Metab
Auteurs principaux: Kabadi, Shruti V, Stoica, Bogdan A, Zimmer, Danna B, Afanador, Lauriaselle, Duffy, Kara B, Loane, David J, Faden, Alan I
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671122/
https://ncbi.nlm.nih.gov/pubmed/26154869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.165
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